Hand cream or lotion after washing your hands?
You wash your hands, reach for the keyboard and feel the skin over your knuckles pull. Two things matter when choosing what to put on: how dry your hands feel and which texture you will actually use again after the next wash.

Start with the moment you apply it
After rinsing, pat your hands with a clean towel. While the skin is still slightly damp, spread moisturizer over the backs of your hands, your fingers and around your nails. Keep the tube beside the towel if you usually forget until you are already back at your desk.
Choose a texture for the job ahead
A fluid lotion spreads easily. If the lotion you own feels comfortable when you return to work and you reach for it after the next wash, keep using it. A cream is generally thicker. For hands that become very dry with repeated washing, the American Academy of Dermatology recommends a fragrance-free hand cream or ointment.
Try what is already in the cupboard
Pick one spot you notice during the day, such as the skin over a knuckle. After your next wash, apply your usual moisturizer to slightly damp hands. Notice how that spot feels when you return to what you were doing. If you already own a richer cream, try it after another similar wash. A texture you like at bedtime may be less convenient just before handling paperwork.
What changes after hand sanitizer?
Let sanitizer dry completely before adding hand cream. Slightly damp skin is the cue after washing with water. If painful cracks, bleeding or persistent irritation make ordinary tasks uncomfortable, ask a healthcare professional for individual advice.
Dermatologists’ advice on caring for hands after washing · American Academy of Dermatology